Feline polynucleotide vaccine formula

Details Feline polynucleotide vaccine formula Feline polynucleotide vaccine formula

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/70 (2006.01) C07K 14/015 (2006.01) C07K 14/03 (2006.01) C07K 14/08 (2006.01) C07K 14/145 (2006.01) C07K 14/15 (2006.01) C07K 14/155 (2006.01) C07K 14/165 (2006.01)

Patent

CA 2261345

A cat vaccine formula including at least three polynucleotide vaccine valencies that each include a plasmid containing a cat pathogen valency gene capable of being expressed in vivo in host cells. Said valencies are selected from the group which consists of feline leukaemia virus, panleukopenia virus, infectious peritonitis virus, coryza virus, calicivirus disease virus, feline immunodeficiency virus and optionally rabies virus. Said plasmids include one or more genes per valency, and said genes are selected from the group which consists of env and gag for feline leukaemia, VP2 for panleukopenia, modified S, M and N for infectious peritonitis, gB and gD for coryza, capsid for calicivirus disease, env and gag/pro for feline immunodeficiency and G for rabies.

La formule de vaccin pour chat comprenant au moins trois valences de vaccin polynucléotidique comprenant chacune un plasmide intégrant, de manière à l'exprimer in vivo dans les cellules hôtes, un gène d'une valence de pathogène de chat, ces valences étant choisies parmi le groupe consistant en virus de la leucémie féline, virus de la panleucopénie, virus de la péritonite infectieuse, virus du coryza, virus de la calicivirose, virus de l'immunodéficence féline et éventuellement virus de la rage, les plasmides comprenant, pour chaque valence, un ou plusieurs des gènes choisis parmi le groupe consistant en env et gag pour la leucémie féline, VP2 pour la panleucopénie, S modifié, M, N pour la péritonite infectieuse, gB et gD pour le coryza, capside pour la calicivirose, env et gag/pro pour l'immunodéficience féline et G pour la rage.

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