Feline t-lymphotropic lentivirus

Details Feline t-lymphotropic lentivirus Feline t-lymphotropic lentivirus

C - Chemistry, Metallurgy

07

K

167/130, 167/170

C07K 16/10 (2006.01) A61K 39/21 (2006.01) C07K 14/155 (2006.01) C12N 7/00 (2006.01) C12N 7/01 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1341439

-30- Compositions derived from a novel viral isolate designated feline T-lymphotropic lentivirus (FTLV) include the whole virus; proteins, polypeptides and, polynucleotide sequences derived from the virus; and antibodies to antigenic sites on the virus. These compositions are useful in a variety of techniques for the detection of and vaccination against FTLV. Detection methods disclosed include immunoassays for both the virus and antibodies to the virus, and the use of polynucleotide probes to detect the viral genome. Vaccines include both wholly and partially inactivated viruses and subunit vaccines.. Whole, live virus is also useful as a model system for predicting the behavior of human immunodeficiency virus (HIV).

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