Female hormone-containing patch

Details Female hormone-containing patch Female hormone-containing patch

A - Human Necessities

61

K

A61K 31/565 (2006.01) A61K 9/70 (2006.01) A61K 47/14 (2006.01) A61K 47/16 (2006.01) A61K 47/32 (2006.01) A61P 3/06 (2006.01) A61P 9/10 (2006.01) A61P 15/12 (2006.01) A61P 19/10 (2006.01) A61P 25/28 (2006.01) A61P 43/00 (2006.01) A61K 47/12 (2006.01) A61K 47/18 (2006.01)

Patent

CA 2494915

It is intended to provide a female hormone-containing patch wherein the active ingredient can be highly soluble in a pressure-sensitive adhesive layer, the active ingredient is not adsorbed by the substrate and the patch per se can well follow up with the irregularities on the skin face or body movements. Namely, a patch for external use which contains a female hormone such as a follicular hormone estradiol and/or its derivative or a progestational hormone noretisteron and/or its derivative. This patch comprises an acrylic pressure- sensitive adhesive containing from 0.01 to 1% by weight of an isocyanate corsslinking agent as an essential component.

La présente invention se rapporte à un timbre adhésif contenant une hormone femelle, dans lequel le principe actif peut être fortement soluble dans une couche adhésive autocollante, ledit principe actif n'est pas adsorbé par le substrat et le timbre en tant que tel pouvant suivre parfaitement les irrégularités de la surface de la peau ou les mouvements corporels. L'invention se rapporte notamment à un timbre adhésif pour usage externe qui contient une hormone femelle, une hormone folliculaire telle que l'oestradiol et/ou son dérivé ou une hormone progestative telle que la norethistérone et/ou son dérivé. Ce timbre adhésif comprend un adhésif autocollant acrylique contenant de 0,01 à 1 % en poids d'un agent de réticulation contenant un isocyanate en tant que composant principal.

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