C - Chemistry – Metallurgy – 12 – M
Patent
C - Chemistry, Metallurgy
12
M
341/1, 341/111
C12M 1/36 (2006.01) G06F 15/46 (1985.01)
Patent
CA 1232050
FERMENTATION CONTROL SYSTEM Abstract of the Disclosure A unitary control system controls a plurality of individual digital control systems for fermenter units operating independently of each other in res- ponse to a multiplicity of measured variables representing the reaction rates and end products of each fermenter unit. The energy input quantities to each unit are controlled independently either locally or from a master control unit to achieve optimum fermentation conditions. Each of the plurality of fermentation systems, running under widely varying reaction conditions, is operated to produce any selected microorganism under substantially differing, or substantially identical process reaction conditions. The individual fermenter control system shown in Figure 2 includes an executive program using a high speed microprocessor bus for operating data storage, program storage and signal processing and an application program using a low speed input and output bus for continuously monitoring and transmitting measured condition data and end effecter control data on a sequential basis. Operator intervention for modifying program values or end effecter operation without system upset is provided to both the local, microprocessor computer and the central, minicomputer controller. In Fig. 2 the temperature system includes measuring the temperature of culture 14 by resistive thermodetector 33. Cooling water from line 34 is supplied through control valve 40 to heat exchanger coil 30 in tank 15. To maintain a given temperature the cooling water may also be heated by electrical coil 31. The water is recirculated from heat exchanger 32 to coil 30 by pump 36 through line 27. The temperature of cooling water circulated to tank heat exchanger coil 30 is measured by another RTD 35, and current flow through electrical heater 31 in heat exchanger 32 is measured by ammeter 37. Water passing through heat exchanger 32 either flows out through return line 29 or is recirculated by pump 36.
471455
Merrill Roy D.
Zeitlin James A.
Borden Ladner Gervais Llp
Novartis Vaccines And Diagnostics Inc.
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