Fermentation method for the preparation of testolactone by...

C - Chemistry – Metallurgy – 12 – P

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C12P 33/02 (2006.01) C12P 33/16 (2006.01)

Patent

CA 2538098

The present invention relates to a microbial method for the simultaneous dehydrogenation and oxidation of 4-androsten-3,17-dione to produce 17a-oxo-D- homo-1,4-androstadiene-3,17-dione in high yield and high substrate concentrations, by means of filamentous Fusarium species.

La présente invention se rapporte à un procédé microbien permettant la déshydrogénation et l'oxydation simultanées de la 4-androsten-3,17-dione pour la production de la 17a-oxo-D-homo-1,4-androstadiène-3,17-dione avec un rendement élevé et des concentrations élevées dans le substrat, au moyen d'espèces de Fusarium filamenteuses.

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