Fermentation of cephamycin c

C - Chemistry – Metallurgy – 12 – P

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195/97

C12P 19/00 (2006.01) C12P 35/08 (2006.01)

Patent

CA 1064419

ABSTRACT OF THE DISCLOSURE Increased yields of the known and useful antibiotic cephamycin C [7-(D-5-amino-5-carboxyvaleramido)- 3-(carbamoyloxymethyl)-7-methoxy-3-cephem-4-carboxylic acid] are obtained by the addition of D- or DL-arginine, D- or DL-ornithine and/or one of several polyamines; or D- or DL-lysine in combination with one of several polyamines to fermentation media composed of complex organic nutrients.

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