Fermentation preparation of l-isoleucine

Details Fermentation preparation of l-isoleucine Fermentation preparation of l-isoleucine

C - Chemistry, Metallurgy

12

P

195/134.7

C12P 13/06 (2006.01)

Patent

CA 1155780

Ref. 01-5862 FERMENTATIVE PREPARATION OF L-ISOLEUCINE Abstract of the Disclosure L-isoleucine is prepared by cultivation of an analogue-resistant mutant of Brevibacterium thiogenitalis in an aqueous nutrient medium under aerobic conditions in the presence of from 0.001 to 15 w/v percent of a post-threonine precursor for L-isoleucine. The cultivation is preferably carried out at about 30°C and at a pH of 5 to 4. L-isoleucine is recovered from the fermentation broth.

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