Fermentation process for epothilones

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/53 (2006.01) C12N 1/21 (2006.01) C12N 9/02 (2006.01) C12P 17/08 (2006.01) C12P 17/16 (2006.01) C12P 17/18 (2006.01)

Patent

CA 2416159

Desoxyepothilone compounds are produced by fermentation of an epothilone microorganism in the presence of a P450 enzyme inhibitor.

La présente invention concerne la production de composés à base de désoxyépothilone par fermentation d'un microorganisme épothilonique en présence d'un inhibiteur de l'enzyme P450.

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