Fermentation process for preparation of...

C - Chemistry – Metallurgy – 12 – P

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C12P 17/06 (2006.01) C07D 309/30 (2006.01) C12N 1/20 (2006.01) C12P 19/02 (2006.01)

Patent

CA 2129416

ABSTRACT OF THE DISCLOSURE A process is provided herein for the production of hypocholesteremic compounds, e.g., Lovastatin or Mevastatin. The process comprises fermenting a micro-organism of the genus Coniothyrium, e.g., Coniothyrium fuckelii, in a suitable medium containing specified quantities of glucose, corn starch, soybean flour, meat extract, peptone and sodium, potassium and magnesium salts, the medium having a slightly acidic, and then recovering such compounds therefrom.

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