Fermentation process for the production of pyrimidine...

Details Fermentation process for the production of pyrimidine... Fermentation process for the production of pyrimidine...

C - Chemistry, Metallurgy

12

N

C12N 1/21 (2006.01) C12N 9/00 (2006.01) C12N 9/02 (2006.01) C12N 9/10 (2006.01) C12N 9/12 (2006.01) C12N 9/16 (2006.01) C12P 19/38 (2006.01)

Patent

CA 2070826

DNA coding for at least one enzyme that causes the accumulation of a pyrimidine deoxyribonucleoside is used, in con- junction with metabolic mutations or heterologous DNA coding for metabolic enzymes that also increase pyrimidine deoxyribon- ucleoside production, to engineer cultured cells to express a pyrimidine deoxyribonucleoside (PdN) in recoverable quantities, pro- viding a commercially useful fermentation source for PdNs.

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