C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 17/18 (2006.01) B01D 15/08 (2006.01) C07D 493/04 (2006.01) C12P 17/16 (2006.01)
Patent
CA 2318818
The invention relates to a process for concentrating epothilones in culture media, a process for the production of epothilones, a process for separating epothilones A and B and a strain obtained by mutagenesis for the production of epothilones, as well as aspects related thereto. Crystal forms of epothilone B are also described.
L'invention concerne un procédé permettant de concentrer des épothilones dans un milieu de culture, un procédé destiné à produire des épothilones, un procédé visant à séparer des épothilones A et B, et une souche obtenue par mutagenèse, conçue pour produire des épothilones. L'invention concerne également différents aspects liés à ces procédés, ainsi que des formes cristallines d'épothilone B.
Frank Petersen
Hofmann Hans
Kusters Ernst
Mahnke Marion
Memmert Klaus
Fetherstonhaugh & Co.
Novartis Ag
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