Fertility enhancement

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/685 (2006.01) A61K 31/135 (2006.01) A61K 31/34 (2006.01) A61K 31/41 (2006.01) A61K 31/415 (2006.01) A61K 31/425 (2006.01) A61K 31/55 (2006.01) A61K 31/557 (2006.01) A61K 31/60 (2006.01) A61K 45/00 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2054197

2054197 9013299 PCTABS00002 The present invention relates to a method of enhancing implantation of an embryo within the uterus of a female mammal. The method comprises administering an amount of a PAF antagonist, effective to enhance implantation, to the mammal. The invention also relates to a method of increasing the level of PAF around an embryo in the uterus of a female mammal by administering to the mammal an amount of a PAF antagonist sufficient to inhibit PAF catabolism. Desirably the PAF antagonist is administered together with PAF or a homologue or analogue thereof. The invention also provides compositions comprising a PAF antagonist together with PAF or a homologue or analogue thereof, and a process for preparing the same.

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