Fetal testing for prediction of low birth weight

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2328955

Methods, assays and kits are disclosed for detecting a mother's or a fetus's susceptibility to an adverse pregnancy outcome such as low birth weight. The methods comprise obtaining a biological sample from a patient and determining the presence or absence of an IL-1 allele 2 of a marker that is associated with an adverse pregnancy outcome.

L'invention concerne des méthodes, des dosages et des trousses de détection de la susceptibilité d'une mère ou d'un foetus de présenter une issue défavorable de la grossesse telle qu'un poids faible à la naissance. Les méthodes consistent à prélever un échantillon biologique sur un patient et à déterminer la présence ou l'absence d'un allèle 2 d'IL-1 d'un marqueur associé à une issue défavorable de la grossesse.

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