Fexofenadine polymorphs and processes of preparing the same

Details Fexofenadine polymorphs and processes of preparing the same Fexofenadine polymorphs and processes of preparing the same

C - Chemistry, Metallurgy

07

D

C07D 211/22 (2006.01) A61K 31/445 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2537257

Anhydrous crystalline fexofenadine hydrochloride Form C, crystalline fexofenadine acetate monohydrate Form D, crystalline fexofenadine acetate dihydrate Form E and crystalline fexofenadine free base monohydrate Form F, processes of preparing the same, pharmaceutical compositions thereof, therapeutic uses thereof and methods of treatment therewith.

L'invention concerne l'hydrochlorure de forme C de la fexofenadine cristalline anhydrique, le monohydrate d'acétate de forme D de la fexofenadine cristalline, le dihydrate d'acétate de forme D de la fexofenadine cristalline et le monohydrate de base libre de forme F de la fexofenadine cristalline. L'invention concerne également leurs procédés de préparation, leurs compositions pharmaceutiques, leurs utilisations thérapeutiques et leurs procédés de traitement.

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