Fgf-peceptor agonist dimeric compounds

A - Human Necessities – 61 – K

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A61K 31/435 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2633057

FGF receptor agonist compounds corresponding to the general formula: M<SUB>1</SUB>-L-M<SUB>2</SUB> in which M<SUB>1</SUB> and M<SUB>2</SUB>, which may be identical or different, each represent, independently of one another, a monomer unit M, and L represents a linker group which covalently links M<SUB>1</SUB> and M<SUB>2</SUB>, wherein said monomer unit corresponds to the general formula M which follows: (I). Preparation process and therapeutic use.

Composés agonistes des récepteurs FGFs répondant à la formule générale : M1-L-M2 dans laquelle M1 ou M2 identiques ou différents représentent chacun indépendamment l'un de l'autre une unité monomère M et L représente un groupe de liaison qui lie M1 et M2 de façon covalente, avec ladite unité monomère répond à la formule générale M qui suit :(I) Procédé de préparation et application en thérapeutique.

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