Fgf21 mutants and uses thereof

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/50 (2006.01) A61K 38/16 (2006.01) A61K 38/18 (2006.01) A61K 47/48 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) C07K 19/00 (2006.01) C12N 15/18 (2006.01)

Patent

CA 2726589

The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides, pharmaceutical compositions comprising FGF21 mutant polypeptides, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.

L'invention porte sur des molécules d'acide nucléique codant pour des polypeptides mutants FGF21, sur des polypeptides mutants FGF21, sur des compositions pharmaceutiques comprenant des polypeptides mutants FGF21, et sur des procédés pour traiter des troubles métaboliques à l'aide de tels acides nucléiques, de tels polypeptides ou de telles compositions pharmaceutiques.

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