Fgfr binding peptides

Details Fgfr binding peptides Fgfr binding peptides

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) A61K 38/17 (2006.01) A61P 25/28 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2570267

The present invention relates to new peptide compounds capable of direct binding to fibroblast growth factor receptor (FGFR) and activating said receptor. The compounds of the invention comprise peptide fragments of the neural cell adhesion molecule (NCAM) derived from the fibronectin type-III module 1 (F3, 1) of NCAM. Peptide sequences of the invention are capable of stimulating learning and memory and/or neurite outgrowth and/or neural cell survival. Peptide sequences and compounds comprising thereof, according to the invention, may be beneficially used for treatment and/or prevention of different pathological conditions wherein FGFR and/or NCAM play a role in pathology and/or recovery from disease. Accordingly, pharmaceutical compositions comprising the peptide sequences and compounds of the invention are also in the scope of protection.

L'invention concerne des nouveaux composés peptidiques capables de se lier directement au récepteur du facteur de croissance des fibroblastes (FGFR) et d'activer ce récepteur. Ces composés contiennent des fragments peptidiques de la molécule d'adhérence cellulaire neuronale (NCAM) issue de la molécule 1 de type III de fibronectine (F3, 1) de NCAM. Des séquences peptidiques de l'invention peuvent stimuler l'apprentissage et la mémoire et/ou l'excroissance de neurites et/ou la survivance cellulaire neuronale. Des séquences peptidiques et des composés les contenant peuvent être utilisés de manière bénéfique dans le traitement et/ou la prévention de conditions pathologiques différentes dans lesquelles FGFR et/ou NCAM jouent un rôle dans la pathologie et/ou la récupération de maladies. Par conséquent, des compositions pharmaceutiques contenant les séquences peptidiques et les composés de l'invention font également l'objet d'une protection.

Affiliated with

Also associated with

Rating

Fgfr binding peptides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fgfr binding peptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fgfr binding peptides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1448709