G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/543 (2006.01) A61B 5/00 (2006.01) A61M 31/00 (2006.01) G01N 33/542 (2006.01) G01N 33/566 (2006.01) G01N 33/66 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2583908
A device for sensing analyte concentration, and in particular glucose concentration, in vivo or in vitro is disclosed. A sensing element is attached to the distal end of an optical conduit, and comprises at least one binding protein adapted to bind with at least one target analyte. The sensing element further comprises at least one reporter group that undergoes a luminescence change with changing analyte concentrations. Optionally, the optical conduit and sensing element may be housed within a cannulated bevel.
L'invention concerne un dispositif pour détecter une concentration d'analyte, et en particulier une concentration en glucose, in vivo ou in vitro . Un élément de détection est fixé sur l'extrémité distale d'un conduit optique, et comprend au moins une protéine de liaison conçue pour se lier à au moins un analyte cible. L'élément de détection comprend également au moins un groupe rapporteur subissant un changement de luminescence avec des concentrations d'analyte changeantes. Eventuellement, le conduit optique et l'élément de détection peuvent être compris à l'intérieur d'un biseau canulé.
Alarcon Javier
Herdman Christopher
Jacobson Ross W.
Keith Steven
Weidemaier Kristin
Becton Dickinson And Company
Gowling Lafleur Henderson Llp
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