A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 24/00 (2006.01) A61L 27/22 (2006.01) A61P 19/08 (2006.01)
Patent
CA 2686820
A composition for use in bone healing and bone regeneration in the form of a viscoelastic hydrogel gel or liquid formulation comprising fibrinogen, thrombin and an inorganic component comprising a strontium (Sr) containing compound and/or possibly another metal such as a calcium containing compound. The strontium containing compound can be dissolved in the thrombin solutions or added to the clot in crystalline particulate form. Upon mixing the components, gelation takes place to form a matrix. The composition may also comprise an iodine-containing compound which acts as a plasticizer.
La présente invention concerne une composition qui sert à guérir et régénérer les os et se présente sous la forme d'un hydrogel viscoélastique ou d'une préparation liquide contenant du fibrinogène, de la thrombine et un composé inorganique comprenant du strontium (Sr) renfermant un composé et/ou éventuellement un autre métal, tel qu'un composé contenant du calcium. Le composé contenant du strontium peut être dissout dans les solutions de thrombine ou ajouté au caillot sous une forme particulaire cristalline. Le mélange des composants produit une gélification qui génère une matrice. La composition peut également renfermer un composé contenant de l'iode qui agit tel un plastifiant.
Barry John J.
Goessl Andreas
Zimmer Gerald
Baxter Healthcare S.a.
Baxter International Inc.
Sim & Mcburney
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