Fibrin gel for controlled release of tgf-beta and uses thereof

Details Fibrin gel for controlled release of tgf-beta and uses thereof Fibrin gel for controlled release of tgf-beta and uses thereof

A - Human Necessities

61

K

A61K 47/42 (2006.01) A61K 38/17 (2006.01) A61K 38/18 (2006.01) A61K 38/48 (2006.01) A61L 24/10 (2006.01) A61P 9/00 (2006.01) A61P 19/00 (2006.01) A61P 21/00 (2006.01)

Patent

CA 2675157

The present invention relates, in general, to fibrin sealants, which contain transforming growth factor-beta (TGF- .beta.) for controlled release in situ for therapeutic applications, including musculoskeletal disorders, such as bone and cartilage disorders, soft tissue disorders and cardiovascular diseases.

La présente invention concerne, en général, des adhésifs de fibrine, qui contiennent un facteur de croissance transformant bêta (TGF-.beta.) pour une libération contrôlée in situ pour des applications thérapeutiques, comprenant des troubles musculosquelettiques, tels que des troubles osseux et du cartilage, des anomalies des tissus mous et des maladies cardiovasculaires.

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