Fibrin sealant delivery method

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/48 (2006.01) A61B 17/00 (2006.01) A61L 24/10 (2006.01) A61L 27/00 (2006.01) A61L 25/00 (1990.01)

Patent

CA 2117495

The present invention relates to a method for the formulation of fibrin sealant in a single delivery system. The method involves mixing a fibrinogen/Factor XIII precipitate solution with thrombin under conditions such that thrombin clotting activity is inhibited and said mixture is applied to a body site under conditions which activate the thrombin to convert fibrinogen into fibrin sealant. A single device, syringe or container, can be used to apply the fibrin sealant formulation.

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