Fibrin-targeted inhibitors of thrombin

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 14/815 (2006.01) C07K 16/36 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 15/13 (2006.01) C12N 15/15 (2006.01) C12N 15/57 (2006.01)

Patent

CA 2161772

A chimeric molecule that contains a fibrin-binding portion of an antibody covalently linked to an inhibitor of thrombin, which molecule is administered to inhibit thrombus formation and growth.

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