Fibrinogen assays using dry chemical reagents containing...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/56 (2006.01) B01L 3/00 (2006.01) G01N 33/49 (2006.01) G01N 33/86 (2006.01) G01N 35/00 (2006.01)

Patent

CA 2087033

An apparatus and a method for performing a fibrinogen assay are disclosed. The reaction slide bears a sample well (22) for receiving a liquid sam- ple and a reaction chamber (24) in fluid communi- canon with the sample well. The reaction chamber contains a dry reagent matrix in which is embedded a plurality of magnetic particles. A whole blood or blood derived sample added to the sample well is introduced simultaneously into the reaction dram- ber where it solubilizes the reagent, freeing the magnetic particles and allowing them to move in an oscillating pattern. This oscillating pattern is opti- cally monitored to measure the concentration of clottable fibrinogen in the sample.

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