Fibrinogen purification

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/75 (2006.01) A61K 38/36 (2006.01) A61L 24/10 (2006.01) C07K 1/36 (2006.01)

Patent

CA 2497796

The present invention relates to a process for purifying fibrinogen, which comprises one or more process steps in which one or more contaminating proteins are depleted by negative chromatography and/or negative adsorption using cation exchanger, hydrophobic gel and/or dye gel. In addition, the invention relates to the fibrinogen which is obtained by the process of the invention and which is notable for improved stability, and to the production and use of pharmaceutical preparations comprising this fibrinogen.

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