C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 295/155 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07D 209/08 (2006.01) C07D 211/22 (2006.01) C07D 211/34 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 215/227 (2006.01) C07D 263/34 (2006.01) C07D 277/56 (2006.01) C07D 333/34 (2006.01) C07D 333/38 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 491/048 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2246756
Fibrinogen receptor antagonists of the general formula (I): X-A-Y-Z-B, and which includes, for example, the compounds of formula (IV), are useful for inhibiting the binding of fibrinogen to blood platelets, inhibiting the aggregation of blood platelets, treating thrombus formation or embolus formation, and preventing thrombus or embolus formation.
Antagoniste des récepteurs de fibrinogènes de la formule générale: X-A-Y-Z-B (I), incluant, par exemple, des composés de la formule (IV), utiles pour inhiber la liaison d'un fibrinogène aux plaquettes sanguines ou l'agrégation des plaquettes sanguines, et pour traiter ou prévenir la formation d'un thrombus ou d'un embole.
Duggan Mark E.
Fisher Thorsten E.
Hartman George D.
Perkins James J.
Wai John
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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