Fibroblast growth factor-10

Details Fibroblast growth factor-10 Fibroblast growth factor-10

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A61K 31/70 (2006.01) A61K 38/18 (2006.01) A61K 48/00 (2006.01) C07K 14/50 (2006.01) C07K 16/22 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2183961

Disclosed are human FGF-10 polypeptides and DNA (RNA) encoding such FGF-10 polypeptides. Also provided is a procedure for producing such polypeptide by recombinant techniques. Also disclosed are methods for utilizing such polypeptide for stimulating re- vascularization, for treating wounds and prevent neuronal damage. Antagonists against such polypeptides and their use as a therapeutic to prevent abnormal cellular proliferation, hyper-vascular diseases and epithelial lens cell proliferation are also disclosed. Diagnostic methods for detecting mutations in the FGF-10 coding sequence and alterations in the concentration of FGF-10 protein in a sample derived from a host are also disclosed.

L'invention concerne des polypeptides humains facteur-10 de croissance du fibroblaste (FGF-10) ainsi que l'ADN (ARN) codant lesdits polypeptides FGF-10. L'invention concerne également une procédure de production de ces polypeptides par des techniques de recombinaison. De plus, l'invention concerne des procédés d'utilisation de ce polypeptide afin de stimuler la revascularisation, afin de traiter des lésions et de prévenir une détérioration des neurones. L'invention concerne aussi des antagonistes contre ces polypeptides ainsi que leur utilisation thérapeutique afin de prévenir une prolifération cellulaire anormale, des maladies hypervasculaires ainsi que la prolifération de cellules épithéliales du cristallin. En outre, l'invention concerne des procédés de diagnostic déstinés à détecter des mutations dans la séquence codant le FGF-10, ainsi que des modifications de la concentration de protéines du FGF-10 dans un échantillon dérivé d'un hôte.

Affiliated with

Also associated with

Rating

Fibroblast growth factor-10 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fibroblast growth factor-10, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fibroblast growth factor-10 will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1860576