C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 38/18 (2006.01) A61K 38/22 (2006.01) A61K 48/00 (2006.01) A61P 1/16 (2006.01) A61P 3/00 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 7/02 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 15/00 (2006.01) A61P 17/00 (2006.01) A61P 19/00 (2006.01) A61P 19/02 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07K 14/47 (2006.01) C07K 14/50 (2006.01) C07K 16/18 (2006
Patent
CA 2384089
The present invention is directed to novel polypeptides belonging to the fibroblast growth factor family and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Furthermore, methods of treating obesity are provided.
L'invention concerne des nouveaux polypeptides appartenant à la famille des facteurs de croissance du fibroblaste, ainsi que des molécules d'acides nucléiques codant ces polypeptides. L'invention concerne encore des vecteurs et cellules hôtes comprenant ces séquences d'acides nucléiques, des molécules de polypeptides chimères comprenant les polypeptides de l'invention, condensés à des séquences de polypeptides hétérologues, des anticorps se liant aux polypeptides de l'invention, ainsi que des procédés de production desdits polypeptides. L'invention concerne enfin des procédés de traitement de l'obésité.
Stewart Timothy A.
Tomlinson Elizabeth
Genentech Inc.
Smart & Biggar
LandOfFree
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