Fibroblast growth factor-23 molecules and uses thereof

Details Fibroblast growth factor-23 molecules and uses thereof Fibroblast growth factor-23 molecules and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 9/00 (2006.01) A61K 38/18 (2006.01) C07K 14/50 (2006.01) C07K 16/22 (2006.01) C12N 15/62 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2398603

The present invention provides Fibroblast Growth Factor-23 (FGF-23) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing FGF-23 polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with FGF-23 polypeptides.

L'invention concerne des polypeptides du facteur 23 de croissance de fibroblastes et des molécules d'acides nucléiques les codant. L'invention concerne aussi des agents liants sélectifs, des vecteurs, des cellules hôtes et des procédés pour produire des polypeptides FGF-23. L'invention concerne aussi des compositions pharmaceutiques et des procédés pour le diagnostic, le traitement, l'amélioration et/ou la prévention de maladies, troubles et états associés aux polypeptides FGF-23.

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