Fibroblast growth factor (fgf)-based stabilized compositions...

Details Fibroblast growth factor (fgf)-based stabilized compositions... Fibroblast growth factor (fgf)-based stabilized compositions...

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61K 31/715 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2048638

A novel stabilized composition is provided herein. The stabilized composition includes an agent having a cell and tissue regenerating activity. The agent comprises at least one functionalized, substituted dextran containing the following functions, namely carboxymethyl, benzylamide or benzylamide sulphonate, in association with at least one of the following: an acid FGF; a basic FGF; a derivative thereof; an analogue thereof; a fragment thereof, the fragment thereof having a biological activity. The agent is capable of at least partially restoring the biological activity of the acid and/or basic FGF/FGFs which have been inactivated by prolonged storage or temperature. Novel uses for this stabilized composition are also provided.

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