Fibroblast growth factor receptor-3 (fgfr-3) inhibitors and...

Details Fibroblast growth factor receptor-3 (fgfr-3) inhibitors and... Fibroblast growth factor receptor-3 (fgfr-3) inhibitors and...

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01)

Patent

CA 2741127

The present invention relates to an isolated antibody or fragment thereof, which specifically binds to human FGFR-3(IIIb) and FGFR-3 (IIIc), or mutant forms thereof. Further embodiments include pharmaceutical compositions comprising the antibody and methods of using the antibody to treat cancer. X18531

La présente invention concerne un anticorps isolé ou un fragment de celui-ci, qui se lie spécifiquement à FGFR-3(IIIb) et FGFR-3 (IIIc) humains, ou des formes mutantes de ceux-ci. Dautres modes de réalisation comprennent des compositions pharmaceutiques comprenant lanticorps et des procédés dutilisation de lanticorps pour traiter un cancer. X18531

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