Fibronectin binding protein; monoclonal antibody and their...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/31 (2006.01) A61K 39/40 (2006.01) C07K 1/22 (2006.01) C07K 14/31 (2006.01) C07K 16/12 (2006.01) C07K 16/46 (2006.01) C12N 1/21 (2006.01) C12N 5/12 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2155413

A monoclonal antibody (Mab), or a fragment thereof, that binds to one or more epitopes of a matrix binding protein and an isolated D1-D4 polypeptide from a Staphylococcus aureus Fbp and their use in the prevention of adhesion of bacteria, in particular gram positive bacteria, to extracellular matrix proteins on in-dwelling devices or to matrix proteins in wounds.

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