Fibronectin-containing ophthalmic solution, method of...

A - Human Necessities – 61 – K

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A61K 38/39 (2006.01) A61K 9/00 (2006.01) A61K 47/18 (2006.01)

Patent

CA 2083232

1023-19 ABSTRACT A stable and soluble multi-dose ophthalmic solution is disclosed. The solution contains fibronectin, an amino acid, a sugar, and a lower alkyl p-hydroxybenzoate. A method of treatment of ophthalmic wounds employing the ophthalmic solution, a process for preparing fibronectin for ophthalmic use, a method of lyophilizing an aqueous solution of fibronectin free of albumin, a method for inhibiting bacterial growth in an ophthalmic solution while preserving the cellular adhesion and wound healing activities of fibronectin, and a method of treatment of ophthalmic wounds administering a wound-healing accelerator solution are also disclosed.

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