Fibronectin-modified ecm tissue graft constructs and methods...

Details Fibronectin-modified ecm tissue graft constructs and methods... Fibronectin-modified ecm tissue graft constructs and methods...

A - Human Necessities

61

L

A61L 27/36 (2006.01) A61K 38/39 (2006.01)

Patent

CA 2584015

Described are modified submucosa and other extracellular matrix materials incorporating an amount of bound, exogenous fibronectin. Further described are such materials also having an amount of exogenous heparin bound to the exogenous fibronectin, and also potentially an amount of an exogenous bioactive material, such as a growth factor, bound to the exogenous heparin. Such materials may be used in methods for the treatment of wounds in patients.

L'invention concerne des matières modifiées de sous-muqueuses et d'autres matériaux de matrice extracellulaires qui comprennent une certaine quantité de sang et de fibronectine exogène. Elle concerne également des matériaux qui comprennent une certaine quantité d'une héparine exogène liée à la fibronectine exogène, ainsi qu'éventuellement une quantité d'un matériau bioactif exogène tel que la facteur de la croissance, lié à l'héparine exogène. Ces matériaux peuvent s'utiliser dans des procédés destinés aux traitement des blessures chez les patients.

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