C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/78 (2006.01) A61K 9/00 (2006.01) A61K 38/17 (2006.01) C12N 15/12 (2006.01) C40B 30/04 (2006.01) C40B 40/10 (2006.01) C40B 50/06 (2006.01)
Patent
CA 2752211
A protein scaffold based on a consensus sequence of the tenth fibronectin type III (FN3) repeat from human fibronectin, including isolated nucleic acids that encode a protein scaffold, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. In particular, protein scaffold molecules binding to IgG bassed on the consensus sequence have been identified as useful for diagnostic and/or therapeutic applications.
La présente invention concerne un support protéique basé sur une séquence fondamentale de la dixième unité de répétition de la fibronectine de type III (FN3) provenant de la fibronectine humaine, comprenant des acides nucléiques isolés qui codent pour un support protéique, des vecteurs, des cellules hôtes, et ses procédés de fabrication et d'utilisation ayant des applications dans des compositions de diagnostic et/ou thérapeutiques, des procédés et des dispositifs. En particulier, les molécules du support protéique se liant à l'IgG basée sur la séquence fondamentale ont été identifiées comme étant utiles pour des applications de diagnostic et/ou thérapeutiques.
Jacobs Steven
O'neil Karyn
Janssen Biotech Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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