Fibrous scaffold for use in soft tissue engineering

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 11/08 (2006.01) C12N 5/071 (2010.01) A61F 2/44 (2006.01) A61L 27/36 (2006.01) A61L 27/40 (2006.01) A61L 27/54 (2006.01) A61L 27/56 (2006.01) A61L 27/58 (2006.01) C08G 18/67 (2006.01) C08L 75/16 (2006.01) C12N 11/00 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2678422

The present invention relates to a fibrous scaffold for use as a substrate in soft tissue applications, in particular for preparing annulus fibrosus (AF) tissue. In aspects, the present invention also relates to an engineered biological material comprising AF tissue; constructs comprising one or more engineered biological materials; methods for producing the biological materials and constructs; and methods of using the biological materials and constructs.

La présente invention concerne un échafaudage fibreux pour une utilisation comme un substrat dans des applications de tissus mous, notamment pour la préparation de tissu d'anneaux fibreux (AF) de disque intervertébral. Dans certains aspects, la présente invention concerne également un matériau biologique reconstitué comprenant un tissu d'anneaux fibreux; des constructions comprenant un ou plusieurs matériaux biologiques reconstitués; des procédés de production de matériaux biologiques et de constructions; et des procédés d'utilisation de matériaux biologiques et de constructions.

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