Filamentous hemagglutinin of b. pertussis

Details Filamentous hemagglutinin of b. pertussis Filamentous hemagglutinin of b. pertussis

C - Chemistry, Metallurgy

12

N

195/1.22, 195/1.

C12N 15/31 (2006.01) A61K 39/10 (2006.01) A61P 31/00 (2006.01) C07K 14/235 (2006.01) C12N 1/20 (2006.01) C12N 9/12 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1341123

Nucleic acid and protein compositions are provided from B. pertussis which may find use in diagnosis, prevention and therapy of whooping cough. Particularly, an open reading frame encoding filamentous hemagglutinin precursors provided, with the intact protein for the filamentous hemagglutinin portion thereof, can be expressed in a wide variety of hosts, for use in the production of antibodies, for immunodiagnosis or therapy, or as vaccines for prophylactic purposes.

614474

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