Fill liquid composition for ibuprofen capsule and capsule...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/192 (2006.01) A61K 9/08 (2006.01) A61K 9/48 (2006.01) A61K 47/08 (2006.01) A61K 47/10 (2006.01)

Patent

CA 2419147

A fill liquid composition for capsules is produced by mixing ibuprofen, polyethylene glycol, water and terpenoid selected from menthol, limonene, borneol, dl-camphor, peppermint oil and so forth, and optionally one or more agents selected from antipyretic analgesic, anti-histamine, antitussive, expectorant, sympathetic nerve stimulant, central stimulant, hypnotic sedative and antiphlogistic, and solubilizing agent, viscous agent, pH adjuster, coloring agent, and the like, in order to exhibit the effects that the prevention of bitterness of ibuprofen and the quick-activeness of ibuprofen are consistently achieved.

L'invention concerne des préparations en gélules produites au moyen de solutions destinées à être mises en gélules, contenant de l'ibuprofène, du polyéthylène glycol, de l'eau et des terpènes (menthol, limonène, bornéol, dl-camphre, huile de menthe, etc.), éventuellement en association avec un ou plusieurs agents pharmaceutiques choisis parmi les analgésiques antipyrétiques, les antihistamines, les antitussifs, les expectorants, les stimulants sympathiques, les analeptiques, les hypnotiques sédatifs, les anti-inflammatoires, les solubilisants, les épaississants, les agents correcteurs de pH, les colorants etc.. L'invention vise par ailleurs à éliminer l'amertume de l'ibuprofène et à produire un effet immédiat desdites solutions.

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