Film coatings containing fine particle size detackifiers and...

A - Human Necessities – 61 – K

Patent

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A61K 9/28 (2006.01)

Patent

CA 2760037

The present invention is directed to film coating compositions for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which contain a fine particle size detackifier. The film coating compositions can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the polymer is either polyvinyl alcohol or a copolymer of polyvinyl alcohol. Aqueous suspensions comprising the inventive film coating compositions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed.

La présente invention concerne des compositions d'enrobage par film devant être utilisées sur des formes pharmaceutiques destinées à une administration par voie orale comme des comprimés et autres substrats pouvant être ingérés par voie orale qui contiennent un antiadhésif à fines particules. Les compositions d'enrobage par film peuvent être appliquées soit directement sur un substrat, soit après enrobage du substrat avec une sous-couche. Dans des aspects préférés, le polymère est soit un alcool polyvinylique, soit un copolymère de l'alcool polyvinylique. L'invention concerne également des suspensions aqueuses comprenant les compositions d'enrobage par film de l'invention, des procédés d'application des enrobages sur les substrats et les substrats enrobés eux-mêmes.

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