Filtration membrane and process for producing the membrane

Details Filtration membrane and process for producing the membrane Filtration membrane and process for producing the membrane

C - Chemistry, Metallurgy

08

J

18/24

C08J 9/28 (2006.01) B01D 69/02 (2006.01) B01D 69/08 (2006.01) B01D 71/56 (2006.01) D01D 5/24 (2006.01)

Patent

CA 1226708

ABSTRACT A fillration membrane, especially adapted for use in hemofiltration as well as filtration of infusion solu- tions. The membrane, in the form of a hollow fiber, is made of a polymer which is soluble in a polar, non-protonic organic solvent. The most preferred polymer for the membrane material is polyamide. Characterizing for the membrane is high ultrafiltration rates (permeabilities to water) of up to 500 x 10-4 m1/sec. x cm2 x atm., and impermeability to albumin (Mw 68,000). The membrane is prepared by extruding a polymer solution with a center liquid under conditions such that the volume of polymer solution to volume of center liquid ratio is within the range of from 2:1 to 4:1. Simul- taneously, the inner diameter to wall thickness ratio of the hollow fiber is preferably correlated to the polymer concentration and is set to 150:75 to 280:75 at a polymer concentration of 5 - 20%. The most preferred such cor- relation is 220:75 at a polymer concentration of 11%.

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