Fine-milled colestipol hydrochloride

Details Fine-milled colestipol hydrochloride Fine-milled colestipol hydrochloride

A - Human Necessities

61

K

167/206

A61K 31/785 (2006.01) A61K 9/14 (2006.01)

Patent

CA 1335261

The present invention provides a novel fine milled form of a known pharmaceutical composition, colestipol hydrochloride. This fine milled form of colestipol hydrochloride yields pharmaceutically elegant dosage forms exhibiting increased potency, including non- gritty oral powders and high dose oral tablets (e.g., 1000 mg tablets). Conventional colestipol hydrochloride was heretofore available in spherical granules which produced less elegant (gritty) oral suspensions and oral tablets with substantially lower doses of drug (e.g., ca 500 mg).

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