A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 9/14 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 47/12 (2006.01) A61K 47/18 (2006.01) A61P 17/00 (2006.01)
Patent
CA 2601373
An additive comprising at least one member selected from arginine, trometamol, meglumine, lysine, histidine, monoethanolamine, diethanolamine, triethanolamine, succinic acid, citric acid, tartaric acid, lactic acid and salts thereof. The additive can prevent microparticles of a complex composed of a nucleic acid molecule and collagen from coagulation and is useful for the production of a preparation comprising particles of a complex which has a controlled particle size and is suitable for transport of a nucleic acid.
Additif comprenant au moins un élément sélectionné parmi l~arginine, le trométamol, la méglumine, la lysine, l~histidine, la monoéthanolamine, la diéthanolamine, la triéthanolamine, l~acide succinique, l~acide citrique, l~acide tartrique, l~acide lactique et leurs sels. L~additif peut empêcher les microparticules d~un complexe composé d~une molécule d~acide nucléique et de collagène de coaguler et il est utile pour la production d~une préparation comprenant des particules d~un complexe qui a une taille de particule contrôlée et qui est adéquat pour le transport d~un acide nucléique.
Kishimoto Yoshiko
Maeda Miho
Dainippon Sumitomo Pharma Co. Ltd.
Kirby Eades Gale Baker
Koken Co. Ltd.
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