Fish protein hydrolysate having a bone-stimulating and...

C - Chemistry – Metallurgy – 12 – P

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Details

C12P 21/06 (2006.01) A23J 3/34 (2006.01) A61K 38/01 (2006.01)

Patent

CA 2714155

The present invention relates to a fish protein hydrolysate having a biological activity of interest, in particular an effect on the stimulation and maintenance of bone. The fish protein hydrolysate is characterized in that it is obtained by enzymatic hydrolysis of at least one protein source selected from the fish species Micromesistius poutassou, Clupea harengus, Scomber scombrus, Sardina pilchardus, Trisopterus esmarki, Trachurus spp, Gadus morhua, Pollachius virens, Melanogrammus aeglefinus and Coryphaenoides rupestris, and the species of fish belonging to the order Siluriformes, said enzymatic hydrolysis being carried out by means of an endopeptidase enzyme derived from Bacillus subtilis. The protein hydrolysate according to the invention makes it possible to maintain the bone mass or to stimulate bone growth through stimulation of osteoblast cell growth and inhibition of osteoclast cell growth.

La présente invention concerne un hydrolysat de protéines de poisson présentant une activité biologique d'intérêt, en particulier un effet sur la stimulation et le maintien du capital osseux. L'hydrolysat de protéines de poisson se caractérise en ce qu'il est obtenu par hydrolyse enzymatique d'au moins une source de protéines choisie parmi les espèces de poissons Micromesistius poutassou, Clupea harengus, Scomber scombrus, Sardina pilchardus, Trisopterus esmarki, Trachurus spp,Gadus morhua, Pollachius virens, Melanogrammus aeglefinus, Coryphaenoides rupestris, et de poissons appartenant à l'ordre des siluriformes, ladite hydrolyse enzymatique étant réalisée par une enzyme endopeptidase dérivée de Bacillus subtilis. L'hydrolysatde protéines selon l'invention permet le maintien de la masse osseuse ou la stimulation de la croissance osseuse par une stimulation de la croissance des cellules ostéoblastes et une inhibition de la croissance des cellules ostéoclastes.

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