Fish protein hydrolysate having a satietogenic activity,...

C - Chemistry – Metallurgy – 12 – P

Patent

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Details

C12P 21/06 (2006.01) A23J 3/34 (2006.01) A61K 35/60 (2006.01) A61K 38/01 (2006.01) C07K 14/595 (2006.01)

Patent

CA 2714128

The present invention relates to a fish protein hydrolysate containing molecules capable of exerting a satietogenic activity and of regulating food intake in humans or animals. More specifically, the protein hydrolysate according to the invention enables stimulation of the secretion of endogenous cholescystokinins (CCKs) and of endogenous glucagon-like peptide 1(GLP1) molecules by intestinal cells and the supply of exogenous CCKs. The fish protein hydrolysate according to the invention is obtained by enzymatic hydrolysis of at least one protein source selected from the group composed of the pelagic fish species Micromesistius poutassou, Clupea harengus, Scomber scombrus, Sardina pilchardus, Trisopterus esmarki and Trachurus spp., the demersal fish species Gadus morhua, Pollachius virens, Melanogrammus aeglefinus and Coryphaenoides rupestris, and the species of fish belonging to the order Siluriformes, said enzymatic hydrolysis being carried out by means of a mixture of enzymes comprising endopeptidases derived from Bacillus amyloliquefaciens and from Bacillus licheniformis, or derived from Bacillus amyloliquefaciens, from Bacillus licheniformis and from Aspergillus oryzae.

La présente invention concerne un hydrolysat de protéines de poisson contenant des molécules capables d'exercer une activité satiétogène et de réguler la prise alimentaire chez l'homme ou l'animal. Plus précisément, l'hydrolysat de protéines selon l'invention permet la stimulation de la sécrétion de cholescystokinines (CCK) et de molécules de glucagon-like peptide 1 (GLP1) endogènes par des cellules intestinales et l'apport de CCK exogènes. L'hydrolysat de protéines de poisson selon l'invention est obtenu par hydrolyse enzymatique d'au moins une source de protéines choisie parmi le groupe composé des espèces de poissons pélagiques Micromesistius poutassou, Clupea harengus, Scomber scombrus, Sardina pilchardus, Trisopterus esmarki, Trachurus spp., de poissons démersaux Gadus morhua, Pollachius virens, Melanogrammus aeglefinus, Coryphaenoides rupestris, de poissons appartenant à l'ordre des siluriformes, ladite hydrolyse enzymatique étant réalisée par un mélange d'enzymes comprenant des endopeptidases dérivées de Bacillus amyloliquefaciens et de Bacillus licheniformis ou dérivées de Bacillus amyloliquefaciens, de Bacillus licheniformis et d'Aspergillus oryzae.

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