Fk-506 c -c process intermediates

Details Fk-506 c -c process intermediates Fk-506 c -c process intermediates

C - Chemistry, Metallurgy

07

D

260/549.45, 260/

C07D 263/26 (2006.01) C07C 43/166 (2006.01) C07C 45/28 (2006.01) C07C 45/45 (2006.01) C07C 47/277 (2006.01) C07C 49/255 (2006.01) C07C 259/06 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2012884

7552P/ 3/23/89:F1 17915 TITLE OF THE INVENTION NEW FK-506 C10-C18 PROCESS INTERMEDIATES ABSTRACT OF THE DISCLOSURE A process is described for the improved synthesis of the optically pure C10-C18 fragment of the macrolide structure of the immunosuppressant FK-506. This compound is also useful as an intermediate for preparing FK-506 derivatives.

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