C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/052 (2006.01) A61K 31/352 (2006.01) A61K 31/436 (2006.01) A61K 31/472 (2006.01) C07D 217/16 (2006.01) C07D 217/24 (2006.01) C07D 311/30 (2006.01)
Patent
CA 2584507
The present disclosure provides non-naturally occurring polyphenol compounds that upregulate the expression of Apolipoprotein A-I (ApoA-I). The disclosed compositions and methods can be used for treatment and prevention of cardiovascular disease and related disease states, including cholesterol or lipid related disorders, such as, e.g., atherosclerosis.
La présente invention a trait à des composés polyphénols synthétiques qui assurent une régulation à la hausse de l'expression de l'alipoprotéine A-I (ApoA-I). Les composés et les procédés de l'invention peuvent être utilisés pour le traitement et la prévention de la maladie cardio-vasculaire et des états de maladie associés, comprenant des troubles liés au cholestérol ou aux lipides, tels que, par exemple, l'athérosclérose.
Chiacchia Fabrizio S.
Hansen Henrik C.
Mccaffrey David
Tucker Joseph E. L.
Wong Norman C. W.
Gowling Lafleur Henderson Llp
Resverlogix Corp.
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