Flavin adenine dinucleotide - labeled conjugates for use in...

Details Flavin adenine dinucleotide - labeled conjugates for use in... Flavin adenine dinucleotide - labeled conjugates for use in...

C - Chemistry, Metallurgy

07

H

167/44, 260/8, 1

C07H 19/16 (2006.01) C07H 19/20 (2006.01) C07H 21/00 (2006.01) G01N 33/535 (2006.01) G01N 33/78 (2006.01)

Patent

CA 1128883

ABSTRACT OF THE DISCLOSURE Labeled conjugates of the formula: Image Wherein Riboflavin-(Phos)2-Ribose represents the riboflavin -pyrophosphate-ribose residue in flavin adenine dinueleotide (FAD), ? = 2 through 6, and ?CO)L is flavin adenine dinueleotide ligand, or a binding analog thereof, and is preferably an iodothyronine such as thyroxine, bound through an amide bond; and intermediates produced in the synthesis of such FAD-labeled conjugates. The FAD-labeled conjugates are useful as labeled conjugates in specific binding assays for determining the ligand or a specific binding partner thereto in liquid media such as serum.

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