Flavin adenine dinucleotide-labeled protein and polypeptide...

Details Flavin adenine dinucleotide-labeled protein and polypeptide... Flavin adenine dinucleotide-labeled protein and polypeptide...

C - Chemistry, Metallurgy

07

H

530/15.12

C07H 21/00 (2006.01) C12N 9/04 (2006.01) G01N 33/535 (2006.01)

Patent

CA 1152491

ABSTRACT OF THE DISCLOSURE Flavin adenine dinucleotide-labeled conjugates of the formula: Image wherein Image Ribose represents the riboflavin -pyrophosphate-ribose residue in flavin adenine dinucleotide (FAD), ?NH)L is a protein or polypeptide (e.g., an immuno- globulin) bound through an amino group thereof, n is an integer from 2 through 10, ? is an integer from 1 through 10, and p is on the average from 1 to the number of available amino groups in L. The FAD-labeled conjugates are useful as reagents in specific binding assays (e.g., immunoasssys) to determine the conjugated protein or polypeptide, or a specific binding analog or partner thereof, in liquid medii.

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