Flaviviridae mutants comprising a deletion in the capsid...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/18 (2006.01) C12N 7/04 (2006.01)

Patent

CA 2713400

The present invention relates to a mutant virus of the family flaviviridae, comprising a deletion in the capsid protein of at least 20 successive amino acids, without any further deletion, substitution or insertion mutation except of the amino acids next to the deletion, which may be substituted.

La présente invention concerne un virus mutant de la famille des flavivirus, comprenant une délétion dans la protéine capsidique d'au moins 20 acides aminés successifs, sans aucune autre mutation par délétion, substitution ou insertion, sauf concernant les acides aminés voisins de la délétion, qui peuvent, pour leur part, être substitués.

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