Flavonolignan preparations, especially silymarin preparations

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/335 (2006.01) A61K 35/78 (2000.01)

Patent

CA 2304493

The invention relates to flavonolignan preparations, especially silymarin preparations, which dissolve more easily than pure flavonoids or pure silymarin, to medicaments which contain these preparations and which are used for treating and preventing liver disease, and to a method for producing the preparations without using additional support materials. The inventive flavonolignan preparations are characterised in that they consist of a homogenous liquid mixture of milk thistle extract (Carduus extract) with a high silymarin content, in polyethylene glycol (PEG).

La présente invention porte sur des préparations de flavonolignan, notamment de préparations à base de silymarine, ayant la propriété de se dissoudre plus facilement que des flavonoïdes pures ou de la silymarine pure. Elle porte aussi sur des médicaments contenant ces préparations et utilisée pour le traitement et la prévention de maladies du foie, ainsi que sur un procédé de production de telles préparations ne faisant pas intervenir d'autres substances support. Les préparations de flavonolignan selon l'invention sont caractérisées en ce qu'elles sont composées d'un mélange liquide homogène d'extrait de chardon Marie (extrait de carduus) à teneur élevée en silymarine, dans du polyéthylène-glycol (PEG).

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