Flea and tick octopamine receptor nucleic acid molecules,...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 7/01 (2006.01) C12P 21/02 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2492498

The present invention relates to tick octopamine receptor nucleic acid molecules; to tick octopamine receptor proteins encoded by such nucleic acid molecules; to antibodies raised against such proteins; and to compounds that inhibit the activity of such proteins. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. The present invention also includes inhibitory compounds, particularly those that specifically inhibit tick octopamine receptor activity, as well as the use of such compounds to treat animals.

L'invention concerne des molécules d'acides nucléiques du récepteur de l'octopamine chez les tiques; des protéines du récepteur de l'octopamine chez les tiques codées par lesdites molécules d'acides nucléiques; des anticorps dirigés contre lesdites protéines; et des composés qui inhibent l'activité desdites protéines. L'invention concerne également des procédés de production de ces protéines, molécules d'acides nucléiques, anticorps, et composés inhibiteurs. L'invention concerne en outre des composés inhibiteurs, en particulier ceux qui inhibent l'activité du récepteur d'octopamine chez les tiques, ainsi que l'utilisation desdits composés pour le traitement d'animaux.

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